Current Issue : April - June Volume : 2014 Issue Number : 2 Articles : 4 Articles
This study was aimed at investigating the antioxidant, whitening, and\r\nmoisture-retention properties of Lactobacillus rhamnosus spent culture supernatant (Lr-SCS)\r\nin cosmetic applications. Results reveal that Lr-SCS effectively and gradually scavenges\r\n1,1-diphenyl-2-picrylhydrazyl as well as 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic\r\nacid) radical cations, and increases reducing power in a dose-dependent manner.\r\nAdditionally, Lr-SCS can also suppress tyrosinase activity in vitro and effectively promote\r\nmoisture retention. Heat treatment at 100 �°C for 30 min does not influence the functions of\r\nLr-SCS. We conclude that Lr-SCS can be used effectively in skin care cosmetics....
To develop a new antioxidant, antibacterial and natural cosmetic ingredient\r\nwithout cytotoxicity to skin cells, bioactive molecules contained in Kalanchoe pinnata leaf\r\nmethanolic extract were targeted using semi-preparative HPLC fractionation linked to\r\nbiological activity tests. Chromatographic effluent was collected at the column outlet into\r\na 96 deep-well microplate, filling successively all the wells. After freeze-drying, the\r\nmicroplate was ready to use for different biological tests such as antimicrobial activity on\r\nmicroorganisms, skin cell viability and antioxidant activity on human keratinocyte cells.\r\nThe injection of only 2.64 mg of crude extract into the HPLC system reveals a good\r\ncorrelation between the chromatographic peaks and the different biological activities.\r\nOne fraction is mainly of interest since good antibacterial and antioxidant activities without\r\ncytotoxicity are observed. The analysis of this fraction using mass spectrometry allows the\r\nidentification of glycoside derivatives of quercetin, isorhamnetin and kaempferol. Thus, a\r\ncorrelation between biological activity and the presence of these flavonoids is obtained.\r\nThis screening method allows a rapid fractionation associated with a biological activity\r\nevaluation and a first molecular identification, saving time by limiting sample treatments\r\nand solvent consumption....
Trace amounts of potentially toxic metals can be either intentionally added to cosmetics or present as impurities in the rawmaterials.\r\nIn the present study, the levels of lead, cadmium, nickel, chromium, andmercury have been assessed in 28 body creams and lotions,\r\n10 powders, 3 soaps, 5 eye make-ups, and 4 lipsticks widely available onNigerianmarkets.Theincreases over suggested or mandated\r\nlevels of lead in these creams and lotions ranged from 6.1 to 45.9 and from 1.2 to 9.2mg kg-1 when compared with Cosmetic\r\nIngredients Review Expert Panel 2007 and German safe maximum permissible limit of lead in cosmetics, respectively. About 61%of\r\nthe body cosmetics, the lotions, and the creams contained detectable levels of nickel ranging from1.1 to 6.4ââ?¬â??9.2mg kg-1. Chromium\r\nandmercury were undetected in 100%of the cosmetic product. Taken together, lead and cadmium were high in creams and lotions.\r\nMost of the imported creams and creamy white coloured cosmetics contained higher levels of metal contaminants than the other\r\ncolours. Regulatory Agencies in developing nations should take appropriate action for cosmetics that contain lead and cadmium\r\nbeyond the reference limits....
Multiple emulsions are excellent and exciting potential systems for the delivery of useful cosmetic agents. The work describes\r\nstability of amultiple emulsion for cosmetic purpose, loaded with extract of Camellia sinensis L. (Theaceae) in concentration of 5%.\r\nTheformulation constitutes of cetyl dimethicone copolyol and polyoxyethylene (20) cetyl ether as emulsifiers and was characterised\r\nand monitored for various physicochemical aspects. Centrifugation has no devastating effect on physical destabilization/phase\r\nseparation observed for 30 days.Mean globule sizes ofmultiple droplets were found in the range of 10.29 �± 4.4 ??m to 12.77 �± 5.1 ??m\r\nand of inner droplets were in the range of 0.8 �± 0.4 ??m to 1.6�± 0.8 ??m. All samples exhibited shear thinning behavior with increase\r\nin shear stress. The results of the present study indicate that multiple emulsions can be used as carrier of 5% Camellia sinensis L.\r\nextract to enhance desired effects. The developed physically and chemically stable system is an effective system for targeting skin\r\nlayers; however, long-term stability at elevated temperatures may be needed with suitable modifications, if required....
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